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Two subsets of human marginal zone B cells resolved by global analysis of lymphoid tissues and blood. Science Immunology

Jacqueline H.Y. Siu, Michael J. Pitcher, Thomas J. Tull, Rebekah L. Velounias, William Guesdon, Lucia Montorsi, Charles W. Armitage, Krishnaa T. Mahbubani, Richard Ellis, Pawan Dhami, Katrina Todd, Ulrich D. Kadolsky, Michelle Kleeman, David P. D’Cruz, Kourosh Saeb-Parsy, Mats Bemark, Gavin J. Pettigrew, Jo Spencer

Science Immunology. March 2022

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Human marginal zone B cell development from early T2 progenitors. J Exp Med.

Thomas J. Tull, Michael J. Pitcher, William Guesdon, Jacqueline H. Siu, Cristina Lebrero-Fernández, Yuan Zhao, Nedyalko Petrov, Susanne Heck, Richard Ellis, Pawan Dhami, Ulrich D. Kadolsky, Michelle Kleeman, Yogesh Kamra, David J. Fear, Susan John, Wayel Jassem, Richard W. Groves, Jeremy D. Sanderson, Michael D. Robson, David D’Cruz, Mats Bemark, Jo Spencer

J Exp Med. 2021

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Cryptosporidium parvum Subverts Antimicrobial Activity of CRAMP by Reducing Its Expression in Neonatal Mice. Microorganisms.

William Guesdon, Tiffany Pezier, Sandrine Menard, Alessandra Nicolosi, Yves Le Vern, Anne Silvestre, Julien Diana, Fabrice Laurent, Sonia Lacroix-Lamandé

Microorganisms. 2020

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Targeting the resolvin E1-eicosapentaenoic acid axis improves hyperinsulinemia and hyperglycemia in a host genetic dependent manner. FASEB.

Anandita Pal, Abrar E Al-Shaer, William Guesdon, Maria J Torres, Michael Armstrong, Kevin Quinn, Traci Davis, Nichole Reisdorph, P Darrell Neufer, Espen E Spangenburg, Ian Carroll, Richard P Bazinet, Joan Clària, Saame Raza Shaikh
FASEB. 2019
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Reduced CD27-IgD- B Cells in Blood and Raised CD27-IgD- B Cells in Gut-Associated Lymphoid Tissue in Inflammatory Bowel Disease. Front. Immunol.

Pararasa C, Zhang N, Tull TJ, Chong MHA, Siu JHY, Guesdon W, Chavele KM, Sanderson JD, Langmead L, Kok K, Spencer J, Vossenkamper A.
Front Immunol. 2019 Mar 5
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Frontline Science: A reduction in DHA-derived mediators in male obesity contributes toward defects in select B cell subsets and circulating antibody. J Leukoc Biol.

Crouch MJ, Kosaraju R, Guesdon W, Armstrong M, Reisdorph N, Jain R, Fenton J, Shaikh SR.
J Leukoc Biol. 2019 Aug
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Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue. Nat Commun.

Zhao Y, Uduman M, Siu JHY, Tull TJ, Sanderson JD, Wu YB, Zhou JQ, Petrov N, Ellis R, Todd K, Chavele KM, Guesdon W, Vossenkamper A, Jassem W, D’Cruz DP, Fear DJ, John S, Scheel-Toellner D, Hopkins C, Moreno E, Woodman NL, Ciccarelli F, Heck S, Kleinstein SH, Bemark M, Spencer J.
Nat Commun. 2018 Sep
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Effects of fish oils on ex vivo B-cell responses of obese subjects upon BCR/TLR stimulation: a pilot study. J Nutr Biochem.

Guesdon W, Kosaraju R, Brophy P, Clark A, Dillingham S, Aziz S, Moyer F, Willson K, Dick JR, Patil SP, Balestrieri N, Armstrong M, Reisdroph N, Shaikh SR.
J Nutr Biochem. 2018 Mar
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B Cell Activity Is Impaired in Human and Mouse Obesity and Is Responsive to an Essential Fatty Acid upon Murine Influenza Infection. J Immunol.

Kosaraju R*, Guesdon W*, Crouch MJ*, Teague HL, Sullivan EM, Karlsson EA, Schultz-Cherry S, Gowdy K, Bridges LC, Reese LR, Neufer PD, Armstrong M, Reisdorph N, Milner JJ, Beck M, Shaikh SR.
* R.K, W.G, and M.J.C contributed equally to this work
J Immunol. 2017 Jun
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Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod-induced psoriasis-like inflammation. Eur. J. Immunol.

Pohin M, Guesdon W, Mekouo AA, Rabeony H, Paris I, Atanassov H, Favot L, Mcheik J, Bernard FX, Richards CD, Amiaud J, Blanchard F, Lecron JC, Morel F, Jégou JF.
Eur J Immunol. 2016 Jul
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CCL20 Displays Antimicrobial Activity Against Cryptosporidium parvum, but Its Expression Is Reduced During Infection in the Intestine of Neonatal Mice. J Infect Dis.

Guesdon W, Auray G, Pezier T, Bussière FI, Drouet F, Le Vern Y, Marquis M, Potiron L, Rabot S, Bruneau A, Werts C, Laurent F, Lacroix-Lamandé S.
J Infect Dis. 2015 Oct
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The gut flora is required for the control of intestinal infection by poly(I:C) administration in neonates. Gut Microbes.

Lacroix-Lamandé S, Guesdon W, Drouet F, Potiron L, Lantier L, Laurent F.
Gut Microbes. 2014 Jul
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Intestinal CD103+ dendritic cells are key players in the innate immune control of Cryptosporidium parvum infection in neonatal mice. PLoS Pathog.

Lantier L, Lacroix-Lamandé S, Potiron L, Metton C, Drouet F, Guesdon W, Gnahoui-David A, Le Vern Y, Deriaud E, Fenis A, Rabot S, Descamps A, Werts C, Laurent F.
PLoS Pathog. 2013
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Poly(I:C)-induced protection of neonatal mice against intestinal Cryptosporidium parvum infection requires an additional TLR5 signal provided by the gut flora. J Infect Dis.

Lantier L, Drouet F, Guesdon W, Mancassola R, Metton C, Lo-Man R, Werts C, Laurent F, Lacroix-Lamandé S
J Infect Dis. 2014 Feb
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Intestinal epithelial cells in immune response inducting during cryptosporidium parvum infection: roles of antimicrobial peptides and microRNAs.

William Guesdon under the supervision of Sonia Lacroix-Lamandé
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